Caitlyn ADC has trouble against Vayne (48.3% win rate) based on 2765 games. This is a tough matchup for Caitlyn players.
View detailed statistics below: items, runes, and counter builds for Caitlyn ADC vs Vayne ADC in patch 15.24 (25.24), including win rates and pick rates. With proper study, this can improve your chances of victory up to 73.9% in this matchup.
Current meta showdown: Caitlyn (14.3% pick rate, 4th most popular out of 30 ADC champions) versus Vayne (8.2%, 10th place). These two bot lane titans clash constantly, making matchup mastery a decisive factor in your climb. Every edge matters: In this tough matchup, the proven Lethal Tempo + Presence of Mind combination (60.7% win rate) plus optimal itemization Yun Tal Wildarrows, Infinity Edge, Rapid Firecannon, and Berserker's Greaves boosts your chances from 48.3% to 73.9% - potentially game-changing.
Farm your way back: Caitlyn's superior farming (6.91 vs 6.85/min, 11th among ADC) offers a comeback path. Focus on safe CSing and capitalize on your 0.06 CS/min natural advantage. Damage doesn't equal wins: Caitlyn outputs more damage (898 vs 872/min, 2nd place) but still loses the matchup. The issue likely lies in survivability, mobility, or damage timing rather than raw output. Complete dominance by Vayne: leads in both matchup win rate (51.7%) and KDA (2.20 vs 2.10, 25th vs 27th place). Caitlyn players need exceptional preparation to overcome this counter-pick.
| Caitlyn ADC | Versus | Vayne ADC |
|---|---|---|
| B+ | Tier | S |
| 48.3% | Matchup Winrate | 51.7% |
| 49.36% | Role Winrate | 52.22% |
| #19 | Winrate Rank | #4 |
| 14.3% | Pickrate | 8.2% |
| 2.1 | Average KDA | 2.2 |
| 459 | Gold per Minute | 443 |
| 6.91 | CS/Min | 6.85 |
| 0.28 | Wards per Minute | 0.27 |
| 898 | Damage per Minute | 872 |
Despite the slight difference in effectiveness, in the Caitlyn versus Vayne matchup as ADC, neither champion has an overwhelming advantage. The winner is determined by player skill and understanding the intricacies of the confrontation. Studying this guide will improve your chances of success.
Except for rare builds, Caitlyn deals physical damage. Focus on eliminating enemy carries. Vayne deals mainly physical damage (71.12%), additional items against this damage type may be required against snowballing or aggressive play.
An important advantage of Caitlyn is higher farming statistics (ranked 11th among role champions) (versus 12th for Vayne), which provides a stable gold advantage in extended games and allows faster access to key items. Meanwhile, their higher KDA (2.2 versus 2.1) suggests they participate more effectively in team fights.
In this difficult confrontation, it is critically important for the Caitlyn player to avoid attempts to force trades and all-ins with the Vayne player, as the matchup requires a patient and calculated approach. Extended trades without clear tactical advantage often lead to unfavorable consequences, and ignoring opportunities to receive team support can be a fatal mistake for game progression.






Attacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds…

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.Take…

Gain 0.35% Life Steal for every Legend stack (max 15 stacks). At maximum Legend…

Deal 8% more damage to champions who have less than 40% health.


While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 …

Every 10 min gain AP or AD, adaptive.10 min: + 8 AP or 5 AD 20 min: + 24 AP or …

Increases attack speed by 10%

Grants 9 Attack Damage or 9 Ability Power

Increases health from 10 to 180 HP across levels 1-18


Attacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds…

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.Take…

Gain 0.35% Life Steal for every Legend stack (max 15 stacks). At maximum Legend…

Deal 8% more damage to champions who have less than 40% health.


You get free Slightly Magical Footwear at 12 min, but you cannot buy boots befo…

Biscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until …

Increases attack speed by 10%

Grants 9 Attack Damage or 9 Ability Power

Increases health from 10 to 180 HP across levels 1-18




























