Miss Fortune ADC performs well against Vayne (53.8% win rate) based on 1618 games. This matchup works well for Miss Fortune players.
View detailed statistics below: items, runes, and counter builds for Miss Fortune ADC vs Vayne ADC in patch 15.24 (25.24), including win rates and pick rates. With proper study, this can improve your chances of victory up to 77.3% in this matchup.
Current meta showdown: Miss Fortune (18.2% pick rate, 1st most popular out of 30 ADC champions) versus Vayne (8.2%, 10th place). These two bot lane titans clash constantly, making matchup mastery a decisive factor in your climb. Even tiers, uneven results: Both champions sit at S-tier, but Miss Fortune claims a meaningful 53.8% vs 46.2% advantage. Miss Fortune's kit synergizes better in this specific head-to-head matchup. Optimize for consistency: Press the Attack paired with Triumph (69.4% win rate, 2.7% popularity) provides the stats you need, while the item sequence Bloodthirster > Infinity Edge > Lord Dominik's Regards with Boots of Swiftness delivers 77.3% win rate against Vayne.
Win through macro: Miss Fortune takes the matchup (53.80%) despite falling behind in CS (6.67 vs 6.85/min). Your victories come through roaming, team fighting, and map pressure rather than 1v1 lane dominance. Complete superiority: Miss Fortune dominates both win rate (53.8%) and damage output (901 vs 872/min, 2nd among ADC). The 29 damage/min difference creates massive snowball potential. Statistical dominance: Miss Fortune leads in both matchup win rate (53.8%) and KDA (2.50 vs 2.20) - complete superiority across all metrics.
| Versus | |
|---|---|---|
| S | Tier | S |
| 53.8% | Matchup Winrate | 46.2% |
| 51.86% | Role Winrate | 52.22% |
| #8 | Winrate Rank | #4 |
| 18.2% | Pickrate | 8.2% |
| 2.5 | Average KDA | 2.2 |
| 488 | Gold per Minute | 443 |
| 6.67 | CS/Min | 6.85 |
| 0.29 | Wards per Minute | 0.27 |
| 901 | Damage per Minute | 872 |
The Miss Fortune versus Vayne matchup as ADC is favorable with proper positioning. Use your statistical advantage and prevent the opponent from realizing their potential.
Except for rare builds, Miss Fortune deals physical damage. Focus on eliminating enemy carries. Vayne deals mainly physical damage (71.12%), additional items against this damage type may be required against snowballing or aggressive play.
Consider the farming superiority demonstrated by Vayne, ranking 12th (versus 17th for Miss Fortune) in farming efficiency among champions in this role. This means the opponent can build gold advantages more quickly. Meanwhile, their lower KDA (2.2 versus 2.5) suggests they are less effective in team fights.
Despite the statistical advantage in the matchup, overconfidence can be the main mistake. It is important for the Miss Fortune player to maintain constant pressure on Vayne, not allowing the opponent to safely scale up, and actively use the advantage gained to help their team.
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