Annie Mid has a slight edge over Lissandra (50.8% win rate) based on 508 games. The matchup slightly favors Annie.
View detailed statistics below: items, runes, and counter builds for Annie Mid vs Lissandra Mid in patch 15.24 (25.24), including win rates and pick rates. With proper study, this can improve your chances of victory up to 63.0% in this matchup.
Annie with 1.4% pick rate (43rd place among Mid champions) rarely faces Lissandra, who maintains 2.8% popularity. While this matchup isn't common overall, Lissandra's solid presence in the meta makes understanding it worthwhile when you do play Annie. Optimize for consistency: Electrocute paired with Grisly Mementos (99.3% win rate, 1.0% popularity) provides the stats you need, while the item sequence Malignance > Stormsurge > Rabadon's Deathcap with Sorcerer's Shoes delivers 63.0% win rate against Lissandra.
Win through macro: Annie takes the matchup (50.84%) despite falling behind in CS (5.17 vs 6.10/min). Your victories come through roaming, team fighting, and map pressure rather than 1v1 lane dominance. Complete superiority: Annie dominates both win rate (50.8%) and damage output (799 vs 793/min, 2nd among Mid). The 6 damage/min difference creates massive snowball potential. Intriguing anomaly: Annie wins the matchup (50.8%) despite a lower KDA (2.20 vs 2.30). This suggests you win through macro influence and clutch plays in key moments rather than consistent individual performance.
| Annie Mid | Versus | Lissandra Mid |
|---|---|---|
| B | Tier | B+ |
| 50.8% | Matchup Winrate | 49.2% |
| 50.84% | Role Winrate | 50.66% |
| #25 | Winrate Rank | #28 |
| 1.4% | Pickrate | 2.8% |
| 2.2 | Average KDA | 2.3 |
| 392 | Gold per Minute | 402 |
| 5.17 | CS/Min | 6.10 |
| 0.31 | Wards per Minute | 0.31 |
| 799 | Damage per Minute | 793 |
While statistically Annie is slightly stronger than Lissandra in the mid lane, neither champion has an overwhelming advantage in this matchup. The winner is determined by player skill and understanding the intricacies of the confrontation. Studying this guide will improve your chances of success.
The magic damage that Annie deals remains relevant in the late game. Look for opportunities to initiate or counter-initiate. Meanwhile, Lissandra deals primarily magic damage (88.16%), additional magic resistance may be required.
Consider the farming superiority demonstrated by Lissandra, ranking 43rd (versus 57th for Annie) in farming efficiency among champions in this role. This means the opponent can build gold advantages more quickly. Meanwhile, their higher KDA (2.3 versus 2.2) suggests they participate more effectively in team fights.
Despite the statistical advantage in the matchup, overconfidence can be the main mistake. It is important for the Annie player to maintain constant pressure on Lissandra, not allowing the opponent to safely scale up, and actively use the advantage gained to help their team.






Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive da…

Damaging champions with impaired movement or actions deals 10 - 45 bonus true d…

Collect 1 memento on champion takedowns, up to 18 total.Gain 6 Trinket Haste fo…

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks a…


Your Ultimate has 12% increased damage, healing, and shielding. (AoE damage is …

While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 …

Grants 9 Attack Damage or 9 Ability Power

Grants 9 Attack Damage or 9 Ability Power

Increases health from 10 to 180 HP across levels 1-18


Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive da…

Collect 1 memento on champion takedowns, up to 18 total.Gain 6 Trinket Haste fo…

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bou…


After taking damage from an enemy champion, the next 3 spells or attacks you re…

Gain 6 - 12 (level scaling) Armor and Magic Resist when crowd controlled and fo…

Increases attack speed by 10%

Grants 9 Attack Damage or 9 Ability Power

+65 Health

Increases health from 10 to 180 HP across levels 1-18




























